EksperimentaalneTeadusliku arutelu staadiumis; kliinilist soovitust ei anta

Gut microbiome – decoded

The Vivabioma Shotgun metagenomics test – 80 million reads per sample, 45+ reports on bacteria, fungi, viruses and functional pathways. Stool sample at home, report interpretation and personal recommendations.

Shotgun 80M reads 45+ reports ISO-certified labs Report interpretation
Microbiome test Vivabioma

Informative mapping, not diagnostics or screening

Vivabioma is an informative functional mapping – it is neither a screening nor a diagnostic test – it maps the composition of gut microorganisms and helps you make informed nutrition and lifestyle decisions. It does not replace colonoscopy, calprotectin, PCR for pathogens or a doctor's diagnosis. If you have concerning symptoms (blood in stool, weight loss, persistent pain, fever) – see your family doctor or a gastroenterologist first.

According to international consensus, the clinical utility of microbiome tests remains limited. The test is not used to diagnose disease, prescribe medication or rule out organic disease.

Why the microbiome matters

Your second "organ" weighs up to 2 kg and controls more than you think

The gut microbiome takes part in calibrating the immune system, synthesizing vitamins (K2, B12, folate), producing short-chain fatty acids (butyrate feeds the gut epithelium), synthesizing neurotransmitter precursors (~90% of serotonin precursors are formed in the gut) and shaping the glucose response after meals.

Dysbiosis – a microbial imbalance – is closely linked to insulin resistance, allergies, anxiety and autoimmune diseases. The test doesn't diagnose disease, but helps you understand how to adjust diet, prebiotics and probiotics.

Chronic digestive disorders

Bloating, constipation, diarrhea, IBS-type symptoms

Gut-brain axis

Anxiety, mood disorders, sleep disturbances, “brain fog”

Metabolic dysfunction

Insulin resistance, weight issues, chronic inflammation

Autoimmunity and allergies

Skin problems, eczema, food sensitivities

Microbiome ecosystem

What the report covers

Four blocks, 45+ reports

Diversity and balance

12 reports – bacterial species richness, alpha and beta diversity, ecosystem resilience to stress and antibiotic courses.

Functionality and metabolism

24 reports – how the microbiome produces vitamins (K2, B12, folate), short-chain fatty acids (SCFA – butyrate, propionate) and affects blood sugar response.

Shotgun metagenomics

Technology

Illumina Shotgun metagenomics - 80M reads / sample

  • Detects bacteria, archaea, fungi, viruses and parasites at the strain level – not just genus level as in 16S rRNA tests
  • Functional mapping: metabolic pathways, antibiotic resistance genes (resistome)
  • European labs certified to ISO 17025, 13485 and 15189
  • SSL-encrypted data transfer, GDPR compliance
  • Stool sample shipping included in the price

How the test works

Four steps – most of them at home

The test price includes report interpretation and personal recommendations. If you'd like a separate consultation – choose the combined package.

  1. 1

    Book

    Book your test package online. We’ll send you a Vivabioma sample collection kit with instructions.

  2. 2

    Stool sample at home

    You take a small sample yourself at home (~10 min). You send it back by mail to the lab in Spain – shipping is included in the price.

  3. 3

    Results on average in 8 weeks

    The lab sequences the sample using Illumina Shotgun technology (80M reads/sample). The report arrives by e-mail.

  4. 4

    Report interpretation and recommendations

    Dr Saadi interprets the report in context and prepares personal nutrition and lifestyle recommendations. This is not a separate consultation.

Add-on services

Tests that are added to a consultation

These tests are not ordered separately. During the consultation we discuss whether they add anything in your situation and order them at the appointment if needed.

  • Genetic test (TellmeGen Advanced)

    • €290

      Without a doctor's interpretation

    • €490

      With a written interpretation and doctor's recommendations

  • Gut microbiome analysis (Vivabioma)

    • €290

      Without a doctor's interpretation

    • €390

      With a written interpretation and doctor's recommendations

  • Continuous glucose monitor (CGM)

    • €190

      Includes sensor placement and interpretation of the results

They cannot be booked separately – ordering happens only as part of a doctor's consultation.

Book a consultation

Sample results

What does a microbiome report look like?

The Vivabioma report gives an overview of gut bacterial diversity, important bacterial strains and functional balance. Below is an illustrative example – your results depend on your unique microbiome.

Overall score

Microbiome diversity

6.8/10 Average
LowOptimal

Shannon index + richness score compared to healthy adults

Category

Key bacterial strains

  • Akkermansia muciniphilaLow (0.3%)
  • Faecalibacterium prausnitziiGood (4.2%)
  • Bifidobacterium spp.Borderline
  • Firmicutes / Bacteroidetes ratio1.8 : 1

300+ bacterial species analyzed

Sample data for illustration. Besides the scores, the Vivabioma report includes specific nutrition recommendations (prebiotic fiber, fermented foods, polyphenols) aimed at supporting underrepresented beneficial bacterial strains. In the consultation we review the results together and build a practical 8–12 week action plan for you.

Microbiome change

The microbiome is plastic

Results are assessed in context

Microbiome composition can change over time and is influenced by nutrition, medication and other factors. A single result describes the sampling point and does not by itself establish disease or demonstrate an intervention's effectiveness.

Every previous report is updated in the portal free of charge as Vivabioma's scientific database grows.

Frequently asked questions

Before you book

Reminder: the Vivabioma test is an informative functional mapping study, not a diagnostic medical test. Every significant finding requires a doctor's evaluation, and if there are concerning symptoms, see a gastroenterologist first.

Who this is for

  • Digestive issues
  • Chronic inflammation
  • Refining nutrition strategy

Who this is not for

  • Acute GI infection treatment
  • Anyone unable to wait about 8 weeks

If you’re unsure whether this fits, write to us before booking.

Microbiome test facts

Sample collection
Stool sample taken at home following the Vivabioma kit instructions; collection takes about 10 minutes.
Results timeline
Results arrive on average within 8 weeks of the sample reaching the lab.

The number of visits, visit duration and other terms depend on the selected package.

Why you can trust us

  • Doctor’s appointment

    Appointments are held by Dr Sergey Saadi. Booking and confirmation are always in writing.

  • Booking in the official system

    Appointments are booked in ConnectedOnline – confirmation arrives by email.

  • Your data is protected

    Health data is processed under GDPR and Estonian healthcare requirements.

  • Clear invoice and terms

    The price is shown on the page before you book. Questions: info@synage.ee.

Who this service is not for

Being upfront saves your time and money. This service is not the right choice if:

  • If you have acute gut symptoms (blood in stool, weight loss, fever) – those need a clinical work-up first.
  • If you expect treatment from the test – a microbiome analysis is a map that we build the plan on.
  • For acute problems (severe pain, fever, breathing difficulty, injury) – contact your GP, an on-call doctor or the emergency department.
  • If you expect a replacement for diagnosis and treatment – we work alongside your GP and specialists, not instead of them.
  • If you only want a prescription or a certificate without an assessment – we do not issue those at a prevention visit.

Not sure? Write to us before booking info@synage.ee

Educational content

If you are looking for Dr Saadi’s educational materials – lectures, articles and learning resources – they live on a separate site.

Go to saadiacademy.ee

A separate learning platform

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